Amerindian-specific regions under positive selection harbour new lipid variants in Latinos

Dyslipidemia and obesity are especially prevalent in populations with Amerindian backgrounds, such as Mexican–Americans, which predispose these populations to cardiovascular disease. Here we design an approach, known as the cross-population allele screen (CPAS), which we conduct prior to a genome-wi...

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Detalles Bibliográficos
Autores principales: Ko, Arthur, Cantor, Rita M., Weissglas-Volkov, Daphna, Nikkola, Elina, Reddy, Prasad M. V. Linga, Sinsheimer, Janet S., Pasaniuc, Bogdan, Brown, Robert, Alvarez, Marcus, Rodriguez, Alejandra, Rodriguez-Guillen, Rosario, Bautista, Ivette C., Arellano-Campos, Olimpia, Muñoz-Hernández, Linda L., Salomaa, Veikko, Kaprio, Jaakko, Jula, Antti, Jauhiainen, Matti, Heliövaara, Markku, Raitakari, Olli, Lehtimäki, Terho, Eriksson, Johan G., Perola, Markus, Lohmueller, Kirk E., Matikainen, Niina, Taskinen, Marja-Riitta, Rodriguez-Torres, Maribel, Riba, Laura, Tusie-Luna, Teresa, Aguilar-Salinas, Carlos A., Pajukanta, Päivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062071/
https://www.ncbi.nlm.nih.gov/pubmed/24886709
http://dx.doi.org/10.1038/ncomms4983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062071/
https://www.ncbi.nlm.nih.gov/pubmed/24886709
http://dx.doi.org/10.1038/ncomms4983

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