Evaluation of Bias-Variance Trade-Off for Commonly Used Post-Summarizing Normalization Procedures in Large-Scale Gene Expression Studies

Normalization procedures are widely used in high-throughput genomic data analyses to remove various technological noise and variations. They are known to have profound impact to the subsequent gene differential expression analysis. Although there has been some research in evaluating different normal...

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Detalles Bibliográficos
Autores principales: Qiu, Xing, Hu, Rui, Wu, Zhixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062409/
https://www.ncbi.nlm.nih.gov/pubmed/24941114
http://dx.doi.org/10.1371/journal.pone.0099380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062409/
https://www.ncbi.nlm.nih.gov/pubmed/24941114
http://dx.doi.org/10.1371/journal.pone.0099380

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