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Cannabinoid Receptor 2-63 QQ Variant Is Associated with Persistently Normal Aminotransferase Serum Levels in Chronic Hepatitis C

BACKGROUND AND AIM: To evaluate in anti-HCV-positive patients the clinical impact of the rs35761398 variant of the CNR2 gene leading to the substitution of Gln (Q) of codon 63 of the cannabinoid receptor 2 (CB2) with Arg (R). PATIENTS AND METHODS: 253 consecutive anti-HCV-/HCV-RNA-positive patients...

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Detalles Bibliográficos
Autores principales: Coppola, Nicola, Zampino, Rosa, Sagnelli, Caterina, Bellini, Giulia, Marrone, Aldo, Stanzione, Maria, Capoluongo, Nicolina, Boemio, Adriana, Minichini, Carmine, Adinolfi, Luigi Elio, Maione, Sabatino, Giudice, Emanuele Miraglia Del, Sagnelli, Evangelista, Rossi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062424/
https://www.ncbi.nlm.nih.gov/pubmed/24940753
http://dx.doi.org/10.1371/journal.pone.0099450