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Mechanisms of U87 Astrocytoma Cell Uptake and Trafficking of Monomeric versus Protofibril Alzheimer’s Disease Amyloid-β Proteins

A significant hallmark of Alzheimer’s disease is the formation of senile plaques in the brain due to the unbalanced levels of amyloid-beta (Aβ). However, although how Aβ is produced from amyloid precursor proteins is well understood, little is known regarding the clearance and metabolism of various...

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Detalles Bibliográficos
Autores principales: Li, Yali, Cheng, Deshu, Cheng, Ran, Zhu, Xinyu, Wan, Tao, Liu, Jianmiao, Zhang, Rongying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062444/
https://www.ncbi.nlm.nih.gov/pubmed/24941200
http://dx.doi.org/10.1371/journal.pone.0099939