Osteoblast-Secreted Factors Promote Proliferation and Osteogenic Differentiation of Bone Marrow Stromal Cells via VEGF/Heme-Oxygenase-1 Pathway

The hypoxia-inducible factors (HIFα) are the critical factors that couple angiogenesis and osteogenesis by activating transcription of VEGF in osteoblasts. Mice lacking von Hippel–Lindau gene (Vhl), thus overexpressing HIFα in osteoblasts develop extremely dense and highly vascularized long bones. H...

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Detalles Bibliográficos
Autores principales: Zhang, Lian-Fang, Qi, Jin, Zuo, GuiLai, Jia, Peng, Shen, Xing, Shao, Jin, Kang, Hui, Yang, HuiLin, Deng, LianFu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062480/
https://www.ncbi.nlm.nih.gov/pubmed/24940620
http://dx.doi.org/10.1371/journal.pone.0099946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062480/
https://www.ncbi.nlm.nih.gov/pubmed/24940620
http://dx.doi.org/10.1371/journal.pone.0099946

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