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GADD45a Promoter Regulation by a Functional Genetic Variant Associated with Acute Lung Injury
RATIONALE: Growth arrest DNA damage inducible alpha (GADD45a) is a stress-induced gene we have shown to participate in the pathophysiology of ventilator-induced lung injury (VILI) via regulation of mechanical stress-induced Akt ubiquitination and phosphorylation. The regulation of GADD45a expression...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062486/ https://www.ncbi.nlm.nih.gov/pubmed/24940746 http://dx.doi.org/10.1371/journal.pone.0100169 |