Beat-to-Beat Cycle Length Variability of Spontaneously Beating Guinea Pig Sinoatrial Cells: Relative Contributions of the Membrane and Calcium Clocks

The heartbeat arises rhythmically in the sino-atrial node (SAN) and then spreads regularly throughout the heart. The molecular mechanism underlying SAN rhythm has been attributed by recent studies to the interplay between two clocks, one involving the hyperpolarization activated cation current I(f)...

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Detalles Bibliográficos
Autores principales: Zaniboni, Massimiliano, Cacciani, Francesca, Lux, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062511/
https://www.ncbi.nlm.nih.gov/pubmed/24940609
http://dx.doi.org/10.1371/journal.pone.0100242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062511/
https://www.ncbi.nlm.nih.gov/pubmed/24940609
http://dx.doi.org/10.1371/journal.pone.0100242

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