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Antagonism of cannabinoid receptor 2 pathway suppresses IL-6-induced immunoglobulin IgM secretion

BACKGROUND: Cannabinoid receptor 2 (CB2) is expressed predominantly in the immune system, particularly in plasma cells, raising the possibility that targeting the CB2 pathway could yield an immunomodulatory effect. Although the role of CB2 in mediating immunoglobulin class switching has been reporte...

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Detalles Bibliográficos
Autores principales: Feng, Rentian, Milcarek, Christine A, Xie, Xiang-Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062519/
https://www.ncbi.nlm.nih.gov/pubmed/24913620
http://dx.doi.org/10.1186/2050-6511-15-30