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Gene perturbation and intervention in context-sensitive stochastic Boolean networks

BACKGROUND: In a gene regulatory network (GRN), gene expressions are affected by noise, and stochastic fluctuations exist in the interactions among genes. These stochastic interactions are context dependent, thus it becomes important to consider noise in a context-sensitive manner in a network model...

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Detalles Bibliográficos
Autores principales: Zhu, Peican, Liang, Jinghang, Han, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062525/
https://www.ncbi.nlm.nih.gov/pubmed/24886608
http://dx.doi.org/10.1186/1752-0509-8-60