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CD4(+) T Cell Subset Differentiation and Avidity Setpoint Are Dictated by the Interplay of Cytokine and Antigen Mediated Signals
CD4(+) T cell differentiation has been shown to be regulated by the cytokine milieu present during activation as well as peptide MHC levels. However, the extent to which these two important regulatory signals work in concert to shape CD4(+) T cell function has not been investigated. Using a murine O...
Autores principales: | Shiner, Erin K., Holbrook, Beth C., Alexander-Miller, Martha A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062528/ https://www.ncbi.nlm.nih.gov/pubmed/24940899 http://dx.doi.org/10.1371/journal.pone.0100175 |
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