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Identification and validation of PROM1 and CRTC2 mutations in lung cancer patients

BACKGROUND: Genetic alterations could be responsible lung cancer, the leading cause of worldwide cancer death. METHODS: This study investigated gene mutations in a Han Chinese family of lung cancer using the whole genome exome sequencing and subsequent Sanger sequencing validation and then confirmed...

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Detalles Bibliográficos
Autores principales: He, Yanqi, Li, Yalun, Qiu, Zhixin, Zhou, Bin, Shi, Shaoqin, Zhang, Kui, Luo, Yangkun, Huang, Qian, Li, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062918/
https://www.ncbi.nlm.nih.gov/pubmed/24484648
http://dx.doi.org/10.1186/1476-4598-13-19