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Identification and validation of PROM1 and CRTC2 mutations in lung cancer patients
BACKGROUND: Genetic alterations could be responsible lung cancer, the leading cause of worldwide cancer death. METHODS: This study investigated gene mutations in a Han Chinese family of lung cancer using the whole genome exome sequencing and subsequent Sanger sequencing validation and then confirmed...
Autores principales: | He, Yanqi, Li, Yalun, Qiu, Zhixin, Zhou, Bin, Shi, Shaoqin, Zhang, Kui, Luo, Yangkun, Huang, Qian, Li, Weimin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062918/ https://www.ncbi.nlm.nih.gov/pubmed/24484648 http://dx.doi.org/10.1186/1476-4598-13-19 |
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