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BRCA2 Coordinates the Activities of Cell-Cycle Kinases to Promote Genome Stability

Numerous human genome instability syndromes, including cancer, are closely associated with events arising from malfunction of the essential recombinase Rad51. However, little is known about how Rad51 is dynamically regulated in human cells. Here, we show that the breast cancer susceptibility protein...

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Detalles Bibliográficos
Autores principales: Yata, Keiko, Bleuyard, Jean-Yves, Nakato, Ryuichiro, Ralf, Christine, Katou, Yuki, Schwab, Rebekka A., Niedzwiedz, Wojciech, Shirahige, Katsuhiko, Esashi, Fumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062933/
https://www.ncbi.nlm.nih.gov/pubmed/24835992
http://dx.doi.org/10.1016/j.celrep.2014.04.023