Dynamic Assembly of a Membrane Signaling Complex Enables Selective Activation of NFAT by Orai1

NFAT-dependent gene expression is essential for the development and function of the nervous, immune, and cardiovascular systems and kidney, bone, and skeletal muscle [1]. Most NFAT protein resides in the cytoplasm because of extensive phosphorylation, which masks a nuclear localization sequence. Dep...

Descripción completa

Detalles Bibliográficos
Autores principales: Kar, Pulak, Samanta, Krishna, Kramer, Holger, Morris, Otto, Bakowski, Daniel, Parekh, Anant B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062936/
https://www.ncbi.nlm.nih.gov/pubmed/24909327
http://dx.doi.org/10.1016/j.cub.2014.04.046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062936/
https://www.ncbi.nlm.nih.gov/pubmed/24909327
http://dx.doi.org/10.1016/j.cub.2014.04.046

Ejemplares similares