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Next-generation Sequencing of Advanced Prostate Cancer Treated with Androgen-deprivation Therapy
BACKGROUND: Androgen-deprivation therapy (ADT) is standard treatment for locally advanced or metastatic prostate cancer (PCa). Many patients develop castration resistance (castration-resistant PCa [CRPC]) after approximately 2–3 yr, with a poor prognosis. The molecular mechanisms underlying CRPC pro...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062940/ https://www.ncbi.nlm.nih.gov/pubmed/24054872 http://dx.doi.org/10.1016/j.eururo.2013.08.011 |