Cargando…

Next-generation Sequencing of Advanced Prostate Cancer Treated with Androgen-deprivation Therapy

BACKGROUND: Androgen-deprivation therapy (ADT) is standard treatment for locally advanced or metastatic prostate cancer (PCa). Many patients develop castration resistance (castration-resistant PCa [CRPC]) after approximately 2–3 yr, with a poor prognosis. The molecular mechanisms underlying CRPC pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Rajan, Prabhakar, Sudbery, Ian M., Villasevil, M. Eugenia M., Mui, Ernest, Fleming, Janis, Davis, Mark, Ahmad, Imran, Edwards, Joanne, Sansom, Owen J., Sims, David, Ponting, Chris P., Heger, Andreas, McMenemin, Rhona M., Pedley, Ian D., Leung, Hing Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062940/
https://www.ncbi.nlm.nih.gov/pubmed/24054872
http://dx.doi.org/10.1016/j.eururo.2013.08.011