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Systemic and Cerebral Vascular Endothelial Growth Factor Levels Increase in Murine Cerebral Malaria along with Increased Calpain and Caspase Activity and Can be Reduced by Erythropoietin Treatment

The pathogenesis of cerebral malaria (CM) includes compromised microvascular perfusion, increased inflammation, cytoadhesion, and endothelial activation. These events cause blood–brain barrier disruption and neuropathology and associations with the vascular endothelial growth factor (VEGF) signaling...

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Detalles Bibliográficos
Autores principales: Hempel, Casper, Hoyer, Nils, Kildemoes, Anna, Jendresen, Charlotte Bille, Kurtzhals, Jørgen Anders Lindholm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062992/
https://www.ncbi.nlm.nih.gov/pubmed/24995009
http://dx.doi.org/10.3389/fimmu.2014.00291