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Systemic and Cerebral Vascular Endothelial Growth Factor Levels Increase in Murine Cerebral Malaria along with Increased Calpain and Caspase Activity and Can be Reduced by Erythropoietin Treatment
The pathogenesis of cerebral malaria (CM) includes compromised microvascular perfusion, increased inflammation, cytoadhesion, and endothelial activation. These events cause blood–brain barrier disruption and neuropathology and associations with the vascular endothelial growth factor (VEGF) signaling...
Autores principales: | Hempel, Casper, Hoyer, Nils, Kildemoes, Anna, Jendresen, Charlotte Bille, Kurtzhals, Jørgen Anders Lindholm |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062992/ https://www.ncbi.nlm.nih.gov/pubmed/24995009 http://dx.doi.org/10.3389/fimmu.2014.00291 |
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