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Synthetic induction of immunogenic cell death by genetic stimulation of endoplasmic reticulum stress

Cis-diamminedichloridoplatinum(II) (CDDP), commonly referred to as cisplatin, is a chemotherapeutic drug used for the treatment of a wide range of solid cancers. CDDP is a relatively poor inducer of immunogenic cell death (ICD), a cell death modality that converts dying cells into a tumor vaccine, s...

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Detalles Bibliográficos
Autores principales: Michaud, Mickaël, Sukkurwala, Abdul Qader, Di Sano, Federica, Zitvogel, Laurence, Kepp, Oliver, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063145/
https://www.ncbi.nlm.nih.gov/pubmed/25050202
http://dx.doi.org/10.4161/onci.28276