Dual targeting of CD137 co-stimulatory and PD-1 co-inhibitory molecules for ovarian cancer immunotherapy

We recently demonstrated that simultaneous targeting of CD137 co-stimulatory and programmed cell death 1 (PD-1) co-inhibitory molecules synergistically induced an anticancer immune response in the ID8 syngeneic orthotopic mouse ovarian carcinoma model. We further showed that the therapeutic efficacy...

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Detalles Bibliográficos
Autores principales: Wei, Huafeng, Zhao, Likun, Hellstrom, Ingegerd, Hellstrom, Karl Erik, Guo, Yajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063147/
https://www.ncbi.nlm.nih.gov/pubmed/25050196
http://dx.doi.org/10.4161/onci.28248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063147/
https://www.ncbi.nlm.nih.gov/pubmed/25050196
http://dx.doi.org/10.4161/onci.28248

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