Smac mimetics combined with innate immune stimuli create the perfect cytokine storm to kill tumor cells

A dual immunotherapy approach employing small-molecule inhibitors of apoptosis (IAP) protein antagonists in combination with innate immune stimuli has proven to be highly synergistic and effective in animal tumor models. This strategy overcomes many of the limitations of either single agent therapy...

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Detalles Bibliográficos
Autores principales: Beug, Shawn T, LaCasse, Eric C, Korneluk, Robert G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063156/
https://www.ncbi.nlm.nih.gov/pubmed/25050221
http://dx.doi.org/10.4161/onci.28541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063156/
https://www.ncbi.nlm.nih.gov/pubmed/25050221
http://dx.doi.org/10.4161/onci.28541

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