Intrinsic Conformational Plasticity of Native EmrE Provides a Pathway for Multidrug Resistance

[Image: see text] EmrE is a multidrug resistance efflux pump with specificity to a wide range of antibiotics and antiseptics. To obtain atomic-scale insight into the attributes of the native state that encodes the broad specificity, we used a hybrid of solution and solid-state NMR methods in lipid b...

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Detalles Bibliográficos
Autores principales: Cho, Min-Kyu, Gayen, Anindita, Banigan, James R., Leninger, Maureen, Traaseth, Nathaniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063181/
https://www.ncbi.nlm.nih.gov/pubmed/24856154
http://dx.doi.org/10.1021/ja503145x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063181/
https://www.ncbi.nlm.nih.gov/pubmed/24856154
http://dx.doi.org/10.1021/ja503145x

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