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Intrinsic Conformational Plasticity of Native EmrE Provides a Pathway for Multidrug Resistance
[Image: see text] EmrE is a multidrug resistance efflux pump with specificity to a wide range of antibiotics and antiseptics. To obtain atomic-scale insight into the attributes of the native state that encodes the broad specificity, we used a hybrid of solution and solid-state NMR methods in lipid b...
Autores principales: | Cho, Min-Kyu, Gayen, Anindita, Banigan, James R., Leninger, Maureen, Traaseth, Nathaniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063181/ https://www.ncbi.nlm.nih.gov/pubmed/24856154 http://dx.doi.org/10.1021/ja503145x |
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