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Palladium(II)-Catalyzed Enantioselective C(sp(3))–H Activation Using a Chiral Hydroxamic Acid Ligand

[Image: see text] An enantioselective method for Pd(II)-catalyzed cross-coupling of methylene β-C(sp(3))–H bonds in cyclobutanecarboxylic acid derivatives with arylboron reagents is described. High yields and enantioselectivities were achieved through the development of chiral mono-N-protected α-ami...

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Detalles Bibliográficos
Autores principales: Xiao, Kai-Jiong, Lin, David W., Miura, Motofumi, Zhu, Ru-Yi, Gong, Wei, Wasa, Masayuki, Yu, Jin-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063184/
https://www.ncbi.nlm.nih.gov/pubmed/24815880
http://dx.doi.org/10.1021/ja504196j