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Hes1 Desynchronizes Differentiation of Pluripotent Cells by Modulating STAT3 Activity

Robust development of the early embryo may benefit from mechanisms that ensure that not all pluripotent cells differentiate at exactly the same time: such mechanisms would build flexibility into the process of lineage allocation. This idea is supported by the observation that pluripotent stem cells...

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Detalles Bibliográficos
Autores principales: Zhou, Xinzhi, Smith, Andrew JH, Waterhouse, Anna, Blin, Guillaume, Malaguti, Mattias, Lin, Chia-Yi, Osorno, Rodrigo, Chambers, Ian, Lowell, Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063271/
https://www.ncbi.nlm.nih.gov/pubmed/23649667
http://dx.doi.org/10.1002/stem.1426