An Artifact in LC-MS/MS Measurement of Glutamine and Glutamic Acid: In-Source Cyclization to Pyroglutamic Acid

[Image: see text] Advances in metabolomics, particularly for research on cancer, have increased the demand for accurate, highly sensitive methods for measuring glutamine (Gln) and glutamic acid (Glu) in cell cultures and other biological samples. N-terminal Gln and Glu residues in proteins or peptid...

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Detalles Bibliográficos
Autores principales: Purwaha, Preeti, Silva, Leslie P., Hawke, David H., Weinstein, John N., Lorenzi, Philip L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063328/
https://www.ncbi.nlm.nih.gov/pubmed/24892977
http://dx.doi.org/10.1021/ac501451v

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063328/
https://www.ncbi.nlm.nih.gov/pubmed/24892977
http://dx.doi.org/10.1021/ac501451v

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