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The single-nucleotide polymorphism (GPX4c718t) in the glutathione peroxidase 4 gene influences endothelial cell function: Interaction with selenium and fatty acids

SCOPE: Selenium (Se) is incorporated into selenoproteins as selenocysteine, which requires structures in the 3′-untranslated region (3′-UTR) of selenoprotein mRNAs. The functional consequences of a single nucleotide polymorphism (SNP) within the 3′-UTR of the selenoprotein GPX4 gene (GPX4c718t) was...

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Detalles Bibliográficos
Autores principales: Crosley, Lynne K, Bashir, Shabina, Nicol, Fergus, Arthur, John R, Hesketh, John E, Sneddon, Alan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063342/
https://www.ncbi.nlm.nih.gov/pubmed/23934705
http://dx.doi.org/10.1002/mnfr.201300216