Cytosine Unstacking and Strand Slippage at an Insertion–Deletion Mutation Sequence in an Overhang-Containing DNA Duplex

[Image: see text] Base unstacking in template strands, when accompanied by strand slippage, can result in deletion mutations during strand extension by nucleic acid polymerases. In a GCCC mutation hot-spot sequence, which was previously identified to have a 50% probability of causing such mutations...

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Detalles Bibliográficos
Autores principales: Manjari, Swati R., Pata, Janice D., Banavali, Nilesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063443/
https://www.ncbi.nlm.nih.gov/pubmed/24854722
http://dx.doi.org/10.1021/bi500189g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063443/
https://www.ncbi.nlm.nih.gov/pubmed/24854722
http://dx.doi.org/10.1021/bi500189g

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