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Preventive effects of the angiotensin-converting enzyme inhibitor, captopril, on the development of azoxymethane-induced colonic preneoplastic lesions in diabetic and hypertensive rats

Metabolic syndrome (Mets), including diabetes and hypertension, increases the risk of colorectal cancer via the induction of chronic inflammation, acceleration of oxidative stress, and activation of the renin-angiotensin system. The present study examined the possible inhibitory effects of captopril...

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Detalles Bibliográficos
Autores principales: KOCHI, TAKAHIRO, SHIMIZU, MASAHITO, OHNO, TOMOHIKO, BABA, ATSUSHI, SUMI, TAKAFUMI, KUBOTA, MASAYA, SHIRAKAMI, YOHEI, TSURUMI, HISASHI, TANAKA, TAKUJI, MORIWAKI, HISATAKA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063600/
https://www.ncbi.nlm.nih.gov/pubmed/24959250
http://dx.doi.org/10.3892/ol.2014.2136