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Diagnosis and treatment of carcinosarcoma of the renal pelvis: A case report

Carcinosarcoma is a rare type of renal pelvis malignancy, the diagnosis of which requires the presence of malignant epithelial and mesenchymal components. The prognosis of this disease is extremely poor due to its rapid progression and widespread metastases. The present study describes a case of car...

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Autores principales: DONG, BIAO, ZHANG, JIAN-JIAN, CHEN, CHAO, WANG, YUAN-TAO, ZHAI, XIU-YU, FU, YAO-WEN, ZHOU, HONG-LAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063624/
https://www.ncbi.nlm.nih.gov/pubmed/24959298
http://dx.doi.org/10.3892/ol.2014.2145
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author DONG, BIAO
ZHANG, JIAN-JIAN
CHEN, CHAO
WANG, YUAN-TAO
ZHAI, XIU-YU
FU, YAO-WEN
ZHOU, HONG-LAN
author_facet DONG, BIAO
ZHANG, JIAN-JIAN
CHEN, CHAO
WANG, YUAN-TAO
ZHAI, XIU-YU
FU, YAO-WEN
ZHOU, HONG-LAN
author_sort DONG, BIAO
collection PubMed
description Carcinosarcoma is a rare type of renal pelvis malignancy, the diagnosis of which requires the presence of malignant epithelial and mesenchymal components. The prognosis of this disease is extremely poor due to its rapid progression and widespread metastases. The present study describes a case of carcinosarcoma involving the right renal pelvis in a 73-year-old female who presented with intermittent hematuria and right-flank pain that had persisted for one month. Computed tomography revealed a 2.4×2.5 cm mass in the right renal pelvis, which was diagnosed as a right renal pelvic tumor. Laparoscopic radical resection of the right kidney and ureter was performed. Following surgery, immunohistochemical analysis showed positive reactions for epithelial and mesenchymal markers. Based on these findings, the patient was diagnosed with carcinosarcoma. Thus, immunohistochemical analysis is a critical method for the accurate diagnosis of carcinosarcoma.
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spelling pubmed-40636242014-06-23 Diagnosis and treatment of carcinosarcoma of the renal pelvis: A case report DONG, BIAO ZHANG, JIAN-JIAN CHEN, CHAO WANG, YUAN-TAO ZHAI, XIU-YU FU, YAO-WEN ZHOU, HONG-LAN Oncol Lett Articles Carcinosarcoma is a rare type of renal pelvis malignancy, the diagnosis of which requires the presence of malignant epithelial and mesenchymal components. The prognosis of this disease is extremely poor due to its rapid progression and widespread metastases. The present study describes a case of carcinosarcoma involving the right renal pelvis in a 73-year-old female who presented with intermittent hematuria and right-flank pain that had persisted for one month. Computed tomography revealed a 2.4×2.5 cm mass in the right renal pelvis, which was diagnosed as a right renal pelvic tumor. Laparoscopic radical resection of the right kidney and ureter was performed. Following surgery, immunohistochemical analysis showed positive reactions for epithelial and mesenchymal markers. Based on these findings, the patient was diagnosed with carcinosarcoma. Thus, immunohistochemical analysis is a critical method for the accurate diagnosis of carcinosarcoma. D.A. Spandidos 2014-07 2014-05-13 /pmc/articles/PMC4063624/ /pubmed/24959298 http://dx.doi.org/10.3892/ol.2014.2145 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Articles
DONG, BIAO
ZHANG, JIAN-JIAN
CHEN, CHAO
WANG, YUAN-TAO
ZHAI, XIU-YU
FU, YAO-WEN
ZHOU, HONG-LAN
Diagnosis and treatment of carcinosarcoma of the renal pelvis: A case report
title Diagnosis and treatment of carcinosarcoma of the renal pelvis: A case report
title_full Diagnosis and treatment of carcinosarcoma of the renal pelvis: A case report
title_fullStr Diagnosis and treatment of carcinosarcoma of the renal pelvis: A case report
title_full_unstemmed Diagnosis and treatment of carcinosarcoma of the renal pelvis: A case report
title_short Diagnosis and treatment of carcinosarcoma of the renal pelvis: A case report
title_sort diagnosis and treatment of carcinosarcoma of the renal pelvis: a case report
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063624/
https://www.ncbi.nlm.nih.gov/pubmed/24959298
http://dx.doi.org/10.3892/ol.2014.2145
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