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Inhibition of lung tumor growth in nude mice by siRNA(CD31) targeting PECAM-1

Small interfering RNA (siRNA) provides a promising therapeutic approach in the silencing of disease-causing genes. In the present study, the use of 2′-O-methyl-modified siRNA-cluster of differentiation 31 (siRNA(CD31)), with cationic liposome RNA interference (RNAi)-mate as a carrier, effectively si...

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Detalles Bibliográficos
Autores principales: OUYANG, JIN-SHENG, LI, YU-PING, CHEN, CHENG-SHUI, CHEN, JUN-JIE, CHEN, TONG-KE, CAI, CHANG, YANG, LI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063636/
https://www.ncbi.nlm.nih.gov/pubmed/24959215
http://dx.doi.org/10.3892/ol.2014.2091