Regulatory Mechanisms That Prevent Re-initiation of DNA Replication Can Be Locally Modulated at Origins by Nearby Sequence Elements

Eukaryotic cells must inhibit re-initiation of DNA replication at each of the thousands of origins in their genome because re-initiation can generate genomic alterations with extraordinary frequency. To minimize the probability of re-initiation from so many origins, cells use a battery of regulatory...

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Detalles Bibliográficos
Autores principales: Richardson, Christopher D., Li, Joachim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063666/
https://www.ncbi.nlm.nih.gov/pubmed/24945837
http://dx.doi.org/10.1371/journal.pgen.1004358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063666/
https://www.ncbi.nlm.nih.gov/pubmed/24945837
http://dx.doi.org/10.1371/journal.pgen.1004358

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