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A Quantitative Comparison of Anti-HIV Gene Therapy Delivered to Hematopoietic Stem Cells versus CD4+ T Cells

Gene therapy represents an alternative and promising anti-HIV modality to highly active antiretroviral therapy. It involves the introduction of a protective gene into a cell, thereby conferring protection against HIV. While clinical trials to date have delivered gene therapy to CD4+T cells or to CD3...

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Detalles Bibliográficos
Autores principales: Savkovic, Borislav, Nichols, James, Birkett, Donald, Applegate, Tanya, Ledger, Scott, Symonds, Geoff, Murray, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063676/
https://www.ncbi.nlm.nih.gov/pubmed/24945407
http://dx.doi.org/10.1371/journal.pcbi.1003681