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A Quantitative Comparison of Anti-HIV Gene Therapy Delivered to Hematopoietic Stem Cells versus CD4+ T Cells
Gene therapy represents an alternative and promising anti-HIV modality to highly active antiretroviral therapy. It involves the introduction of a protective gene into a cell, thereby conferring protection against HIV. While clinical trials to date have delivered gene therapy to CD4+T cells or to CD3...
Autores principales: | Savkovic, Borislav, Nichols, James, Birkett, Donald, Applegate, Tanya, Ledger, Scott, Symonds, Geoff, Murray, John M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063676/ https://www.ncbi.nlm.nih.gov/pubmed/24945407 http://dx.doi.org/10.1371/journal.pcbi.1003681 |
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