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An Expanded Notch-Delta Model Exhibiting Long-Range Patterning and Incorporating MicroRNA Regulation

Notch-Delta signaling is a fundamental cell-cell communication mechanism that governs the differentiation of many cell types. Most existing mathematical models of Notch-Delta signaling are based on a feedback loop between Notch and Delta leading to lateral inhibition of neighboring cells. These mode...

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Detalles Bibliográficos
Autores principales: Chen, Jerry S., Gumbayan, Abygail M., Zeller, Robert W., Mahaffy, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063677/
https://www.ncbi.nlm.nih.gov/pubmed/24945987
http://dx.doi.org/10.1371/journal.pcbi.1003655