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Glycosylation Inhibitors Efficiently Inhibit P-Selectin-Mediated Cell Adhesion to Endothelial Cells

Adhesion molecules play a critical role in the adhesive interactions of multiple cell types in sickle cell disease (SCD). We previously showed that anti-P-selectin aptamer efficiently inhibits cell adhesion to endothelial cells (ECs) and permits SCD mice to survive hypoxic stress. In an effort to di...

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Detalles Bibliográficos
Autores principales: Ghoshal, Pushpankur, Rajendran, Mythilypriya, Odo, Nadine, Ikuta, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063735/
https://www.ncbi.nlm.nih.gov/pubmed/24945938
http://dx.doi.org/10.1371/journal.pone.0099363