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Glycosylation Inhibitors Efficiently Inhibit P-Selectin-Mediated Cell Adhesion to Endothelial Cells
Adhesion molecules play a critical role in the adhesive interactions of multiple cell types in sickle cell disease (SCD). We previously showed that anti-P-selectin aptamer efficiently inhibits cell adhesion to endothelial cells (ECs) and permits SCD mice to survive hypoxic stress. In an effort to di...
Autores principales: | Ghoshal, Pushpankur, Rajendran, Mythilypriya, Odo, Nadine, Ikuta, Tohru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063735/ https://www.ncbi.nlm.nih.gov/pubmed/24945938 http://dx.doi.org/10.1371/journal.pone.0099363 |
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