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Dominance Effects of Deleterious and Beneficial Mutations in a Single Gene of the RNA Virus ϕ6

Most of our knowledge of dominance stems from studies of deleterious mutations. From these studies we know that most deleterious mutations are recessive, and that this recessivity arises from a hyperbolic relationship between protein function (i.e., protein concentration or activity) and fitness. He...

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Detalles Bibliográficos
Autores principales: Joseph, Sarah B., Peck, Kayla M., Burch, Christina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063744/
https://www.ncbi.nlm.nih.gov/pubmed/24945910
http://dx.doi.org/10.1371/journal.pone.0097717