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Clinical and Parasitological Protection in a Leishmania infantum-Macaque Model Vaccinated with Adenovirus and the Recombinant A2 Antigen

BACKGROUND: Visceral leishmaniasis (VL) is a severe vector-born disease of humans and dogs caused by Leishmania donovani complex parasites. Approximately 0.2 to 0.4 million new human VL cases occur annually worldwide. In the new world, these alarming numbers are primarily due to the impracticality o...

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Detalles Bibliográficos
Autores principales: Grimaldi, Gabriel, Teva, Antonio, Porrozzi, Renato, Pinto, Marcelo A., Marchevsky, Renato S., Rocha, Maria Gabrielle L., Dutra, Miriam S., Bruña-Romero, Oscar, Fernandes, Ana-Paula, Gazzinelli, Ricardo T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063746/
https://www.ncbi.nlm.nih.gov/pubmed/24945284
http://dx.doi.org/10.1371/journal.pntd.0002853