Spontaneous Colitis in Muc2-Deficient Mice Reflects Clinical and Cellular Features of Active Ulcerative Colitis

BACKGROUND: The colonic mucus layer plays a critical role in intestinal homeostasis by limiting contact between luminal bacteria and the mucosal immune system. A defective mucus barrier in animal models allows bacterial contact with the intestinal epithelium and results in spontaneous colitis. A def...

Descripción completa

Detalles Bibliográficos
Autores principales: Wenzel, Ulf A., Magnusson, Maria K., Rydström, Anna, Jonstrand, Caroline, Hengst, Julia, Johansson, Malin EV., Velcich, Anna, Öhman, Lena, Strid, Hans, Sjövall, Henrik, Hansson, Gunnar C., Wick, Mary Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063762/
https://www.ncbi.nlm.nih.gov/pubmed/24945909
http://dx.doi.org/10.1371/journal.pone.0100217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063762/
https://www.ncbi.nlm.nih.gov/pubmed/24945909
http://dx.doi.org/10.1371/journal.pone.0100217

Ejemplares similares