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The Nuclear Progesterone Receptor Reduces Post-Sigh Apneas during Sleep and Increases the Ventilatory Response to Hypercapnia in Adult Female Mice
We tested the hypothesis that the nuclear progesterone receptor (nPR) is involved in respiratory control and mediates the respiratory stimulant effect of progesterone. Adult female mice carrying a mutation in the nPR gene (PRKO mice) and wild-type controls (WT) were implanted with an osmotic pump de...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063764/ https://www.ncbi.nlm.nih.gov/pubmed/24945655 http://dx.doi.org/10.1371/journal.pone.0100421 |