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The Nuclear Progesterone Receptor Reduces Post-Sigh Apneas during Sleep and Increases the Ventilatory Response to Hypercapnia in Adult Female Mice

We tested the hypothesis that the nuclear progesterone receptor (nPR) is involved in respiratory control and mediates the respiratory stimulant effect of progesterone. Adult female mice carrying a mutation in the nPR gene (PRKO mice) and wild-type controls (WT) were implanted with an osmotic pump de...

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Detalles Bibliográficos
Autores principales: Marcouiller, François, Boukari, Ryma, Laouafa, Sofien, Lavoie, Raphaël, Joseph, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063764/
https://www.ncbi.nlm.nih.gov/pubmed/24945655
http://dx.doi.org/10.1371/journal.pone.0100421