High Levels of SOX5 Decrease Proliferative Capacity of Human B Cells, but Permit Plasmablast Differentiation

Currently very little is known about the differential expression and function of the transcription factor SOX5 during B cell maturation. We identified two new splice variants of SOX5 in human B cells, encoding the known L-SOX5B isoform and a new shorter isoform L-SOX5F. The SOX5 transcripts are high...

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Detalles Bibliográficos
Autores principales: Rakhmanov, Mirzokhid, Sic, Heiko, Kienzler, Anne-Kathrin, Fischer, Beate, Rizzi, Marta, Seidl, Maximilian, Melkaoui, Kerstina, Unger, Susanne, Moehle, Luisa, Schmit, Nadine E., Deshmukh, Sachin D., Ayata, Cemil Korcan, Schuh, Wolfgang, Zhang, Zhibing, Cosset, François-Loic, Verhoeyen, Els, Peter, Hans-Hartmut, Voll, Reinhard E., Salzer, Ulrich, Eibel, Hermann, Warnatz, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063782/
https://www.ncbi.nlm.nih.gov/pubmed/24945754
http://dx.doi.org/10.1371/journal.pone.0100328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063782/
https://www.ncbi.nlm.nih.gov/pubmed/24945754
http://dx.doi.org/10.1371/journal.pone.0100328

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