Evaluation of Anticonvulsant Actions of Dibromophenyl Enaminones Using In Vitro and In Vivo Seizure Models

Epilepsy and other seizure disorders are not adequately managed with currently available drugs. We recently synthesized a series of dibromophenyl enaminones and demonstrated that AK6 and E249 were equipotent to previous analogs but more efficacious in suppressing neuronal excitation. Here we examine...

Descripción completa

Detalles Bibliográficos
Autores principales: Qaddoumi, Mohamed G., Ananthalakshmi, Kethireddy V. V., Phillips, Oludotun A., Edafiogho, Ivan O., Kombian, Samuel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063795/
https://www.ncbi.nlm.nih.gov/pubmed/24945912
http://dx.doi.org/10.1371/journal.pone.0099770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063795/
https://www.ncbi.nlm.nih.gov/pubmed/24945912
http://dx.doi.org/10.1371/journal.pone.0099770

Ejemplares similares