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N-Succinyl-chitosan nanoparticles coupled with low-density lipoprotein for targeted osthole-loaded delivery to low-density lipoprotein receptor-rich tumors

N-Succinyl-chitosan (NSC) was synthesized and NSC nanoparticles (NPs) with loaded osthole (Ost) (Ost/NSC-NPs) were prepared by emulsion solvent diffusion. Subsequently, low-density lipoprotein (LDL)-mediated NSC-NPs with loaded Ost (Ost/LDL-NSC-NPs) were obtained by coupling LDL with Ost/NSC-NPs thr...

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Detalles Bibliográficos
Autores principales: Zhang, Chun-ge, Zhu, Qiao-ling, Zhou, Yi, Liu, Yang, Chen, Wei-liang, Yuan, Zhi-Qiang, Yang, Shu-di, Zhou, Xiao-feng, Zhu, Ai-jun, Zhang, Xue-nong, Jin, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063822/
https://www.ncbi.nlm.nih.gov/pubmed/24966673
http://dx.doi.org/10.2147/IJN.S59799