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N-Succinyl-chitosan nanoparticles coupled with low-density lipoprotein for targeted osthole-loaded delivery to low-density lipoprotein receptor-rich tumors
N-Succinyl-chitosan (NSC) was synthesized and NSC nanoparticles (NPs) with loaded osthole (Ost) (Ost/NSC-NPs) were prepared by emulsion solvent diffusion. Subsequently, low-density lipoprotein (LDL)-mediated NSC-NPs with loaded Ost (Ost/LDL-NSC-NPs) were obtained by coupling LDL with Ost/NSC-NPs thr...
Autores principales: | Zhang, Chun-ge, Zhu, Qiao-ling, Zhou, Yi, Liu, Yang, Chen, Wei-liang, Yuan, Zhi-Qiang, Yang, Shu-di, Zhou, Xiao-feng, Zhu, Ai-jun, Zhang, Xue-nong, Jin, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063822/ https://www.ncbi.nlm.nih.gov/pubmed/24966673 http://dx.doi.org/10.2147/IJN.S59799 |
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