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The H3K27me3 demethylase UTX in normal development and disease

In 2007, the Ubiquitously Transcribed Tetratricopeptide Repeat on chromosome X (UTX) was identified as a histone demethylase that specifically targets di- and tri-methyl groups on lysine 27 of histone H3 (H3K27me2/3). Since then, UTX has been proven essential during normal development, as it is crit...

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Detalles Bibliográficos
Autores principales: Van der Meulen, Joni, Speleman, Frank, Van Vlierberghe, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063824/
https://www.ncbi.nlm.nih.gov/pubmed/24561908
http://dx.doi.org/10.4161/epi.28298