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HARP preferentially co-purifies with RPA bound to DNA-PK and blocks RPA phosphorylation
The HepA-related protein (HARP/SMARCAL1) is an ATP-dependent annealing helicase that is capable of rewinding DNA structures that are stably unwound due to binding of the single-stranded DNA (ssDNA)-binding protein Replication Protein A (RPA). HARP has been implicated in maintaining genome integrity...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063828/ https://www.ncbi.nlm.nih.gov/pubmed/24565939 http://dx.doi.org/10.4161/epi.28310 |