Cell-based assay for the detection of chemically induced cellular stress by immortalized untransformed transgenic hepatocytes

BACKGROUND: Primary hepatocytes, one of the most widely used cell types for toxicological studies, have a very limited life span and must be freshly derived from mice or even humans. Attempts to use stable cell lines maintaining the enzymatic pattern of liver cells have been so far unsatisfactory. S...

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Detalles Bibliográficos
Autores principales: Sacco, Maria Grazia, Amicone, Laura, Catò, Enrica Mira, Filippini, Daniela, Vezzoni, Paolo, Tripodi, Marco
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC406386/
https://www.ncbi.nlm.nih.gov/pubmed/15033002
http://dx.doi.org/10.1186/1472-6750-4-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC406386/
https://www.ncbi.nlm.nih.gov/pubmed/15033002
http://dx.doi.org/10.1186/1472-6750-4-5

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