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Cell-based assay for the detection of chemically induced cellular stress by immortalized untransformed transgenic hepatocytes
BACKGROUND: Primary hepatocytes, one of the most widely used cell types for toxicological studies, have a very limited life span and must be freshly derived from mice or even humans. Attempts to use stable cell lines maintaining the enzymatic pattern of liver cells have been so far unsatisfactory. S...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC406386/ https://www.ncbi.nlm.nih.gov/pubmed/15033002 http://dx.doi.org/10.1186/1472-6750-4-5 |