TLR4 Accessory Molecule RP105 (CD180) Regulates Monocyte-Driven Arteriogenesis in a Murine Hind Limb Ischemia Model

AIMS: We investigated the role of the TLR4-accessory molecule RP105 (CD180) in post-ischemic neovascularization, i.e. arteriogenesis and angiogenesis. TLR4-mediated activation of pro-inflammatory Ly6C(hi) monocytes is crucial for effective neovascularization. Immunohistochemical analyses revealed th...

Descripción completa

Detalles Bibliográficos
Autores principales: Bastiaansen, Antonius J. N. M., Karper, Jacco C., Wezel, Anouk, de Boer, Hetty C., Welten, Sabine M. J., de Jong, Rob C. M., Peters, Erna A. B., de Vries, Margreet R., van Oeveren-Rietdijk, Annemarie M., van Zonneveld, Anton Jan, Hamming, Jaap F., Nossent, A. Yaël, Quax, Paul H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063870/
https://www.ncbi.nlm.nih.gov/pubmed/24945347
http://dx.doi.org/10.1371/journal.pone.0099882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063870/
https://www.ncbi.nlm.nih.gov/pubmed/24945347
http://dx.doi.org/10.1371/journal.pone.0099882

Ejemplares similares