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Priming by Chemokines Restricts Lateral Mobility of the Adhesion Receptor LFA-1 and Restores Adhesion to ICAM-1 Nano-Aggregates on Human Mature Dendritic Cells

LFA-1 is a leukocyte specific β(2) integrin that plays a major role in regulating adhesion and migration of different immune cells. Recent data suggest that LFA-1 on mature dendritic cells (mDCs) may function as a chemokine-inducible anchor during homing of DCs through the afferent lymphatics into t...

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Detalles Bibliográficos
Autores principales: Borgman, Kyra J. E., van Zanten, Thomas S., Manzo, Carlo, Cabezón, Raquel, Cambi, Alessandra, Benítez-Ribas, Daniel, Garcia-Parajo, Maria F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063950/
https://www.ncbi.nlm.nih.gov/pubmed/24945611
http://dx.doi.org/10.1371/journal.pone.0099589